B.S. Biological Engineering, 2008, Cornell University
M. Eng. Biological Engineering, 2009, Cornell University
Matt's current research is on developing a system for in-cell localized mutagenesis in Escherichia coli. This system will target mutations to a particular target region of DNA inside of a live cell while leaving the host strain's background DNA relatively untouched. We are developing this system for use in directed evolution and strain improvement. This work will lead me to projects in strain improvement and phenotype engineering. I have also been involved in work on statistical analysis of mutation rate data from fluctuation test experiments.