Dan Luo is a Professor in the Department of Biological and Environmental Engineering. He works with DNA and RNA as both generic and genetic materials.
Nucleic acids play a critical role in living organisms as the carriers of genetic information. The Luo Lab has been using DNA as a true polymer and has developed generic DNA materials, including tree-shaped DNA, DNA gels, and DNA-nanoparticle hybrid assemblies. With these novel DNA materials, Professor Luo’s group is exploring real-world applications from biology to materials in diagnostics, pharmaceutics, protein production, drug delivery, cell culture, and optoelectronics.
Professor Luo’s teaching emphasizes active learning, and students are exposed to real-world problems and solutions. His current course is BEE 7600 Nucleic Acid Engineering, where students learn the structure-property-function relationship of nucleic acids.
Awards and Honors
- Cornell Outstanding Educator for having most influenced a Merrill Presidential Scholar (2015) Cornell University
- College Fellow (2013) American Institute of Medical and Biological Engineering
- Outstanding Accomplishments in Basic Research (2012) Cornell University College of Agriculture and Life Sciences
- Bill and Melinda Gates Foundation Grand Challenge Diagnostics Award recipient (2011) Bill and Melinda Gates Foundation
- Plenary speaker, 2nd Nano Today Conference (2011) Nano Today
- Xu, X., Jagota, A., Peng, S. M., Luo, D., Wu, M., & Hui, C. Y. (2013). Gravity and Surface Tension Effects on Shape Change of Soft Materials. Langmuir. 29:8665-8671.
- Yang, D. Y., Peng, S. M., Hartman, M. R., Gupton-Campolongo, T., Rice, E. J., Chang, A. K., Gu, Z., Lu, G. Q., & Luo, D. (2013). Enhanced transcription and translation in clay hydrogel and implications for early life evolution. Scientific Reports. 3:3165.
- Tran, T., Cui, J., Hartman, M., Peng, S., Funabashi, H., Duan, F., Yang, D. Y., March, J. C., Lis, J. T., Cui, H., & Luo, D. (2013). A Universal DNA-Based Protein Detection System. Journal of the American Chemical Society. 135:14008-14011.
- Hartman, M. R., Yang, D. Y., Tran, T. T., Lee, K., Kahn, J. S., Kiatwuthinon, P., Yancey, K. G., Trotsenko, O., Minko, S., & Luo, D. (2013). Thermostable Branched DNA Nanostructures as Modular Primers for Polymerase Chain Reaction. Angewandte Chemie: International Edition. 52:8699-8702.
- Hartman, M. R., Ruiz, R. R., Hamada, S., Xu, C. Y., Yancey, K. G., Yu, Y., Han, W., & Luo, D. (2013). Point-of-care nucleic acid detection using nanotechnology. Nanoscale. 5:10141-10154.
- Peer, D., Gianneschi, N., & Luo, D. (2013). Themed issue on nanoparticles in biology. Journal of Materials Chemistry. 1:5174-5176.
- Lee, J. B., Peng, S., Yang, D., Roh, Y. H., Funabashi, H., Park, N., Rice, E. J., Chen, L., Long, R., Wu, M., & Luo, D. (2012). A mechanical metamaterial made from a DNA hydrogel. Nature Nanotechnology. 109:816-820.
- Ruiz, R., Katwuthinon, P., Kahn, J. S., Roh, Y. H., & Luo, D. (2012). Cell-Free Protein Expression from DNA-Based Hydrogel (P-Gel) Droplets for Scale-Up Production. Industrial Biotechnology. 8:372-377.
- Yu, J., Peng, S., Luo, D., & March, J. C. (2012). In vitro 3D human small intestinal villous model for drug permeability determination. Biotechnology and Bioengineering. 109:2173-2178.
- Sharma, A. N., Luo, D., & Walter, M. T. (2012). Hydrological Tracers Using Nanobiotechnology: Proof of Concept. Environmental Science & Technology. 46:8928-8936.
Presentations and Activities
- DNA as Mateterials. A total of 18 invited presentations in year 2010. 2010. world wide.